Ken Olson
for Tri-State Livestock News

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October 17, 2012
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Non-protein nitrogen in protein supplements for beef cows

Anybody that has been paying attention to commodity markets knows that feed costs are high, and they also know that protein feeds such as oilseed meals are disproportionately highest of all. Unfortunately, livestock require protein and a high-protein feed is often the most critical need when the base ingredients in the diet are deficient in protein, such as crop residues or dormant pasture. Less expensive alternatives become important. Luckily, sources of non-protein nitrogen (NPN), such as urea, can be used as a cheaper alternative for ruminants. Thus, urea or other sources of NPN are often incorporated into protein products such as liquid supplements, tubs, blocks, or “cake”. Following are answers to commonly asked questions about NPN:

Why is non-protein nitrogen (NPN) often used in cattle supplements?

Beef cows consuming low-quality forages are almost always deficient in protein. Thus, supplements comprised of high-protein ingredients are recommended over high-energy supplements. The problem is that most high-protein feeds are expensive. Thus, we are constantly searching for less expensive alternative sources of protein. Urea and other sources of NPN offer that opportunity in ruminant animals.

What is NPN?

Nitrogen is a required chemical element of amino acids, which are the basic building blocks of protein. NPN is the source of nitrogen for building of amino acids/protein. Urea is the most commonly used source of NPN in ruminant animal diets.

How does it work?

Animals, including cows, cannot directly use NPN as a source of protein. However, the microorganisms that live in the rumen (one of the compartments of the 4-part ruminant stomach) can convert NPN to protein. In brief, every time a ruminant eats, the population of microbes in the rumen grows and these “bugs” then digest the feed for the ruminant. However, to grow more microbes, the original microbes need protein. They are capable of manufacturing microbial protein from NPN. The microbial protein is then used to grow the new microbes. Once the feed is digested and passes from the rumen through the rest of the stomach and intestines, the microbes ride along with the digested feed and are in turn digested by the cow and used as a source of protein.

How much NPN can be used?

There are limits on the amount of supplemental crude protein that can be NPN. In other words, the rumen microbes need some natural protein to be incorporated into the microbial protein. Extensive research indicates that no more than one-third of the supplemental protein should be NPN. The other two-thirds should be natural protein. For example, in a 30 percent crude protein cake or lick tub, no more than 10 percent of the protein (one-third) should be NPN, and the other 20 percent should be from natural protein.

Why do we need to limit it?

If greater than one-third of the supplemental crude protein is from NPN, digestion of fiber and intake of the low-quality forage will be depressed. Typically, cow nutritional status (measured as body condition score or BCS) and performance (such as pregnancy rate) is similar with up to one-third from NPN to that from an all natural protein source, but both BCS and pregnancy rates decline at higher levels of NPN. Another notable concern is that palatability and consumption of supplements generally declines when NPN levels exceed about 40 percent of supplement protein.

Can NPN based supplements be fed less frequently than every day?

Extensive research indicates that protein supplements do not need to be fed every day to be effective. Because the ruminant animal and its rumen can store excess protein for several days, we can typically reduce feed delivery costs by providing protein supplements as infrequently as every third day. However, this recommendation is based on a supplement containing all natural protein (no NPN). If fed infrequently, the NPN inclusion rate should be no more than 15 percent of the total supplemental protein. In this case, in a 30 percent cake or tub, the NPN should be no more than 4.5 percent (15 percent of 30 percent).


Urea and other sources of NPN can be a viable way to reduce supplemental protein costs for ruminant animals. However, their inclusion rate should be no more than 1/3 of the total protein content of the supplement.

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Tri-State Livestock News Updated Oct 12, 2012 01:38PM Published Jan 28, 2013 01:52PM Copyright 2013 Tri-State Livestock News. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.